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7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8

7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8

7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8
7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8

Large Image :  7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8 Get Best Price

Product Details:
Place of Origin: China
Brand Name: XRD
Certification: GMP
Model Number: 38183-03-8
Payment & Shipping Terms:
Minimum Order Quantity: negotiable
Price: Inquiry for Negotiable
Packaging Details: 1-2 kg / aluminum foil bag, 25kg/ drum, as required
Delivery Time: 1-2days after payment received
Payment Terms: T/T bank, Western Union, Bitcoin, Etc
Supply Ability: 100KG/ Month
Detailed Product Description
CAS: 38183-03-8 Product Name: 7,8-DIHYDROXYFLAVONE
Type: Pharmaceutical Intermediate Appearance: Yellow Powder
Usage: Lowering Blood Pressure Alias: 7,8-dihydroxy-2-phenyl-4-benzopyrone
Assay: 99%min Key Words: 7,8-DIHYDROXYFLAVONE
High Light:

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99% 7,8-Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8

 

Quick Details

7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-moleculeagonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor(BDNF).7,8-DHF is both orally-bioavailable and able to penetrate the blood-brain-barrier.

Medical use:

7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD.

 

Specification:

 

Product Name: 7,8-DIHYDROXYFLAVONE
Synonyms: TIMTEC-BB SBB000930;7,8-DIHYDROXYFLAVONE;7,8-Dihydroxyflavone hydrate
CAS: 38183-03-8
MF: C15H10O4
MW: 254.24
EINECS: 253-812-4
Product Categories: Di-substituted Flavones;Biochemistry;Flavonoids;Inhibitors
Mol File: 38183-03-8.mol
mp 243-246°C
storage temp. Store at +4°C
CAS DataBase Reference 38183-03-8(CAS DataBase Reference)
Chemical Properties Yellow Solid
Biological Activity Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo .

 

 

7,8- Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8 0

 

99% 7,8-Dihydroxyflavone Yellow Powder Lowering Blood Pressure CAS 38183-03-8

 

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