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Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial

Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial

Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial
Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial

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Product Details:
Place of Origin: China
Brand Name: XRD
Certification: GMP
Model Number: 1405-10-3
Payment & Shipping Terms:
Minimum Order Quantity: negotiable
Price: Inquiry for Negotiable
Packaging Details: 1-2 kg / aluminum foil bag, 25kg/ drum, as required
Delivery Time: 1-2days after payment received
Payment Terms: T/T bank, Western Union, Bitcoin, Etc
Supply Ability: 100KG/ Month
Detailed Product Description
CAS: 1405-10-3 Product Name: Neomycin Sulfate
Type: Veterinary Medicine Drugs Appearance: White Powder
Usage: Antibacterial Alias: Neomycin Sulfate 99%
Assay: 99% Neomycin Sulfate Key Words: Neomycin Sulfate Succinate
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Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial



1 . Quick Details:

 

Product Name Neomycin sulfate
Synonyms mycifradin sulfate; o-2,6-diamino-2,6-dideoxy-.beta.-l-idopyranosyl-(1.->3)-o-.beta.-d-ribofuranosyl-(1->5))-o-(2,6-diamino-2,6-dideoxy-.alpha.-d-glucopyranosyl-(1->4))-2-deoxy sulfate
CAS 1405-10-3
EINECS 215-773-1
Molecular formula C23H48N6O17S
Molecular Weight 712.72
Molecular Structure  
General Description white or milk white crystalline powder; odorless or almost odorless; easily soluble in water, slightly soluble in ethanol.
Usage Neomycin Sulphate is an active pharmaceutical ingredient used as an aminoglycoside antibiotic
Packing

0.5kgs/Al-foil bag 1.0kgs/Al-foil bag

2.0kgs/Al-foil bag 5.0 kgs/Al-foil bag

25.0 kgs/drum or upon customers

 


2 . Description:

 

Neomycin sulfate is a kind of aminoglycoside antibiotics. This product to staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active. This article pseudomonas aeruginosa, oxygen resistance.Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin.

 

Neomycin sulphate is a kind of aminoglycoside antibiotics.This product to staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active.This article pseudomonas aeruginosa, oxygen resistance.Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin.Neomycin systemic medication has significant nephrotoxicity and ototoxicity, is currently limited to oral or topical application.

 

3 . Usage:

 

Characteristic of this product is white or kind of white powder;Odourless;Easy to lead wet;Aqueous solution show dextral light.The product easy to dissolve in water, in ethanol, ether, acetone, or almost insoluble in chloroform.Identify

 

(1) take this product for about 10 mg, add water 1 ml dissolves, add 2 ml of hydrochloric acid solution (9-100), heated in water bath for 10 minutes, with 2 ml of 8% sodium hydroxide solution and 2% acetyl acetone solution 1 ml, water bath heating in 5 minutes. After cooling, add to dimethyl amino benzene formaldehyde test solution 1 ml, namely the cherry red.

 

(2) apply the product standard and neomycin, respectively made each 1 ml contains 20 mg of water solution.According to thin layer chromatography (TLC) test, 1 mu l learned these two solution, each point in the same silica gel H thin layer plate (silica gel h1.5o g 6 ml with 0.25% sodium carboxymethyl cellulose solution mixing plate), acetic acid with methanol - - acetone - 8.8% ammonium acetate solution (corresponding: 10:40:) as developing agent, unfolds, dry, dry in 110 ºC for 20 minutes, by hot spraying with 10% sodium hypochlorite solution, the thin layer plate on ventilation, cooling, a spray starch potassium iodide solution (0.5% starch solution contained 0.5 g of potassium iodide in the 100 ml), immediately.Show the main spots by color of test sample solution and location should be the same as the main mark of the standard solution.

 

(3) of this article show the identification of sulphate aqueous reaction.

 

4 . Function:

 

Oral administration can be used to:

(1). Neomycin Sulfate can used to Intestinal infection.
(2). Neomycin Sulfate Can also be used as an adjuvant therapy for bowel preparation before colon surgery or hepatic coma.Neomycin should not be used for the treatment of systemic infections.Mainly for the treatment of trachoma, conjunctivitis, and so on.

 

5 . COA:

 

Test Item Standard Specification Test Data Item Conclusion
Identification a) TLC Complies Qualified
b) Color reaction Complies
c) Sulfate reaction Complies
Infrared absorption According with IR reference spectrum Meets the requirement Qualified
Loss on drying ≤8.0% 3.20%  
Qualified
  5.0-7.5 6.6  
PH Qualified
  ≤0.05% 0.03%  
Residue on ignition Not more than 0.05% of weight Qualified
  The solution is clear Clear Qualified

Substances insoluble in

sodium carbonate

  0.5% max on USP sieve 180(um) Meets the requirement  
Partical size Qualified
  ≤10ppm 10ppm  
Heavy metals The limit is 10ug per g Qualified
Assay Not less than 680 ug/mg 692ug/mg  
Qualified

 

 
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1405-10-3 Neomycin sulfate
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21736-83-4 SPECTINOMYCIN DIHYDROCHLORIDE
64058-48-6 Spectinomycin sulfate tetrahydrate
512-56-1 TMP
50-21-5 Lactic acid
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1981-58-4 Sulfamethazine sodium salt
68-35-9 Sulfadiazine
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Pharmaceutical Intermediates Neomycin Sulfate CAS 1405-10-3 For Antibacterial

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