Pharmaceutical Raw Materials Pregabalin / Treatment Antiepileptic Drugs CAS 148553-50-8

Place of Origin CHINA
Brand Name XRD
Certification GMP
Model Number 148553-50-8
Minimum Order Quantity negotiable
Price Inquiry for Negotiable
Packaging Details 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require
Delivery Time 1-2days after payment received
Payment Terms T/T, Western Union,Bitcoin
Supply Ability 100kg/year

Contact me for free samples and coupons.

Whatsapp:0086 18588475571

Wechat: 0086 18588475571

Skype: sales10@aixton.com

If you have any concern, we provide 24-hour online help.

x
Product Details
Mf C17H17ClN6O3 Cas No. 148553-50-8
Product Name Pregabalin Usage Pharmaceutical Raw Material
Appearance White Powder Assay 99% Pregabalin
Grade Pharmaceutical Grade Application Pharmaceutical Raw Intermediates
High Light

lab research chemicals

,

research chemicals

Leave a Message
Product Description


Pharmaceutical Raw Materials Pregabalin / Treatment Antiepileptic Drugs CAS 148553-50-8

Quick Detail:

Pregabalin
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
Assay: 99%
Appearance: White Crystal Powder
Package: 25kg/drum
Usage: New antiepileptic drugs. Used in the treatment of peripheral neuropathy, or partial seizures


Description:
Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is C8H17NO2 and the molecular weight is 159.23.

Pregabalin is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.

Application
1. Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by under the trade name.

2. Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms, hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster).

3. It is also used to treat fibromyalgia (a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep).

4. Pregabalin is used with other medications to treat certain types of seizures in people with epilepsy.

5. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body.


Efficiency:

Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia).


Dosage of Pregabalin

1. LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure.

2. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.

 


COA:
 

Product name Pregabalin
CAS No. 148553-50-8 Outer Packing 25KG/Cardboard Drum
Production date 2017.6.17 Shelf life 2 years
Standard adopted company standard
Items of analysis Specification Results
Loss on drying ≤0.5% 0.21%
Specific Rotation +10.0°~+13.0° +10.8°
Related Substances Any single impurity ≤0.1% otal impurity ≤0.8% 0.05% 0.10%
Purity By HPLC R-isomer ≤0.15% 0.10
Residue on ignition ≤0.1% 0.05%
Heavy metals ≤10ppm Complies
Chlorides ≤0.05% Complies
Assay 98%~102.0% 99.8%
Conclusion Qualified

 

 

 

 

Pharmaceutical Raw Materials Pregabalin / Treatment Antiepileptic Drugs CAS 148553-50-8 0

 

 

Pharmaceutical Raw Materials Pregabalin / Treatment Antiepileptic Drugs CAS 148553-50-8