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| CAS: | 96829-58-2 | Product Name: | Orlistat |
|---|---|---|---|
| Type: | Weight Loss Powder | Appearance: | White Powder |
| Usage: | Weight Loss | Alias: | Orlipastat |
| Assay: | 99% | Key Words: | Orlistat |
| High Light: | fat loss powder,fat loss steroids |
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Weight Loss Powder Orlistat CAS 96829-58-2 Treating Obesity Slimming
Quick detail
Product name: Orlistat
CAS Numbers: 96829-58-2
Appearance: white needle crystal or powder
Quality standard: CP
Packing specification: 1 kg/bag
Melting point: 45
Purity: 98.0%
MF: C29H53NO5
MW: 495.73
Appearance: white powder
Usage: Used for curing obesity
Introduction
Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.
The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%). Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).
Applications:
| 1. | Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. |
| 2. | Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. |
| 3. | Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug. |
| 4. | Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet. This undigested fat then passes out of your body in your bowel movement. |
| 5. | Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories. |
| 6. | Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). In the United States and the European Union, orlistat is available for sale without a prescription. Generic formulations of orlistat are available in some countries |
Orlistat COA
| tems | Specification Items | Result |
| Appearance | white or almost white crystalline powder,smell less | White crystalline powder |
| Melting Point | 42.0~46.0°C | Confirmed |
| Specific Rotation | -31°~-39°(CHCl3,C=1) | Confirmed |
| Identification | The result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one. | Confirmed |
| Related Substances | ≤ 0.5% | ≤ 0.05% |
| Total impurity | ≤ 1.0% | Confirmed |
| Single impurity | ≤ 0.1% | Confirmed |
| ≤ 290ppm | Confirmed | |
| ≤ 5000ppm | Confirmed | |
| Residual on Ignition | ≤0.1% | Confirmed |
| Sulphate | ≤ 0.05% | Confirmed |
| Heavy Metal | ≤ 20ppm | Confirmed |
| Purity | ≤ 99.0% ~ 99.9% | Confirmed |
Weight Loss Powder Orlistat CAS 96829-58-2 Treating Obesity Slimming
Contact Person: Mr. Bruce Lee
Tel: +8618874586545
Fax: 86-27-8321-4688
