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| CAS: | 915759-45-4 | Product Name: | WAY 316606 |
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| Type: | Anti Hair Loss Powder | Appearance: | White Powder |
| Usage: | Hair Loss Treatment | Alias: | WAY 316606 |
| Assay: | 99% | Key Words: | WAY 316606 |
| High Light: | anti estrogen steroids,hair growing powder |
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Hair Loss Treatment WAY 316606 / CAS 915759-45-4 / way-316606
Quick Details
CAS:
915759-45-4
MF:
C18H19F3N2O4S2
MW:
448.4796696
EINECS:
Synonyms:
BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)-;WAY 316606;WAY-316606;5-(Phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide
Biological Activity
Secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC50 = 0.65 μM); prevents sFRP-1 from interacting with Wnt and thus increases Wnt signaling. Increases total bone area in a murine calvarial organ culture assay.
We are aware of a study in PLOS Biology where WAY-316606 was found to stimulate hair follicle growth. Please note that WAY-316606 from Tocris is for laboratory research use only, and that we will only sell to established scientific businesses and institutes.
WAY 316606WAY 316606 is a sFRP-1 (Secreted frizzled-related proteins) inhibitor (Ki=80 nM); an endogenous antagonist of the secreted glycoprotein Wnt. IC50 value: 80 nM (Kd); 0.65 uM (EC50)Target: sFRP-1 Research showed that WAY 316606 bound to sFRP-1 with a K(D) of 0.08 microM and inhibited it with an EC(50) of 0.65 microM. WAY 316606 increased total bone area in a murine calvarial organ culture assay at concentrations as low as 0.0001 microM. Antiosteoporotic agents.
Contact Person: Mr. Bruce Lee
Tel: +8618874586545
Fax: 86-27-8321-4688
