Hair Loss Solution CB-03-01 / Breezula / 17alpha - Propionate CAS No 19608-29-8
Place of Origin | China |
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Brand Name | XRD |
Certification | GMP |
Model Number | 19608-29-8 |
Minimum Order Quantity | negotiable |
Price | Inquiry for Negotiable |
Packaging Details | 1-2 kg / aluminum foil bag, 25kg/ drum, as required |
Delivery Time | 1-2days after payment received |
Payment Terms | T/T bank, Western Union, Bitcoin, Etc |
Supply Ability | 100KG/ Month |

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xCAS | 19608-29-8 | Product Name | CB-03-01 |
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Type | Pharmaceutical Intermediate | Appearance | White Powder |
Usage | Hair Loss | Alias | 17alpha-propionate |
Assay | 99% | Key Words | CB-03-01 |
High Light | hair growing powder,hair growth powder |
Hair Loss Solution CB-03-01//Breezula//17alpha-propionate CAS No. 19608-29-8
Description:
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
Function:
CB-03-01 is the drug for the treatment of hair loss dwindled. It has same function and application with RU58841 and Setipiprant.
CB-03-01 is a molecule that acts at the level of the skin, blocking dihydrotestosterone (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe. The results of these studies demonstrate that CB-03-01 appears to have potent activity without significant local or systemic side effects.
Application:
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
COA:
Items |
Requirements |
Results |
Appearance: |
White Powder |
White Powder |
Identification |
|
|
HPLC |
IR spectra is consistent with CRS |
Conforms |
Sulphated Ash |
≤0.1% |
0.01% |
Loss on drying |
≤0.5% |
0.38% |
Related substances |
Impurity A ≤0.1% Impurity B ≤0.2% Any other Impurity ≤0.1% All other Impurity A ≤0.2% |
<0.1% <0.2% <0.1% <0.2% |
Heavy metal Pb : Cadmium(Cd) : As : Hg: |
≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm |
<10ppm Conforms 0.3ppm Conforms Negative |
Assay |
≥99% |
99.5% |
Conclusion: |
The product conforms to BP. |
Hair Loss Solution CB-03-01//Breezula//17alpha-propionate CAS No. 19608-29-8