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30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine Sodium

30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine Sodium

30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine Sodium
30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine Sodium

Large Image :  30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine Sodium Get Best Price

Product Details:

Place of Origin: CHINA
Brand Name: XRD
Certification: GMP
Model Number: 30123-17-2

Payment & Shipping Terms:

Minimum Order Quantity: negotiable
Price: Inquiry for Negotiable
Packaging Details: 1-2 Kg / Aluminum Foil Bag, 25kg/ Drum, as Require
Delivery Time: 1-2days after payment received
Payment Terms: T/T, Western Union,Bitcoin
Supply Ability: 5000kg/year
Detailed Product Description
Cas No.: 30123-17-2 Other Names: S-1574
Product NamRopivacainee: Tianeptine Sodium Salt Appearance: White Powder
Assay: 99% Tianeptine Sodium Salt Grade: Pharmaceutical Grade
Storage: Cool Dried Storage Application: Pharmaceutical Raw Intermediates
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30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine sodium

 

 

Basic Info.:

 

Product name: Tianeptine Sodium Salt
Assay: 99%
CAS No: 30123-17-2
Packing Customized: package as you require
M.F.: C21H24ClN2NaO4S
M.W.: 458.93
Appearance: White crystalline powder
Quality Standard: Enterprise Standard
Usage: Treatment of depression.

 

Description:


Tianeptine sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.

 

Application:

 

Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.

Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).

 

Specification:

 
Tests Specifications Results
Description White to yellowish powder, very hygroscopic. Off-white powder, very hygroscopic.
Solubility Freetly soluble In water and methanol and dichloromethane Complies
Identification (1)By IR, To match with working standard Complies
(2)It gives reaction of sodium Complies
Impurities A ≤0.1% Not detected
Related compounds Any impurity ≤0.1% <0.1%
Total impurities ≤0.4% 0.25%
Residual Solvents Acetidin≤ 0.5% Not detected
Dichloromethane≤ 0.06% Not detected
Methanol≤ 0.3% Not detected
Acetone ≤ 0.5% Not detected
Acetonitrile≤0.041% Not detected
Ethanol≤0.5% 0.04%
N, N-dimethylformamide≤0.088% Not detected
Water ≤ 5.0% 1.38%
Assay 99.0%-101.0%(On anhydrous basis) 99.98%
Conclusion Conform to EP8.0
 

 

 

 

 

 

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30123-17-2 Nootropic Powder Research Antidepressant Drugs Tianeptine sodium

 

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