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|Type:||Pharmaceutical Intermediate||Appearance:||White Powder|
raw materials for pharma industry,
intermediates in pharmaceuticals
Febuxostat for Prevention and Treatment of Hyperuricemia and Gout 144060-53-7
Synonyms: 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid; 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Molecular Formula: C16H16N2O3S
Molecular Weight: 316.37
CAS No: 144060-53-7
Melting Point: 238-239 ° C
Boiling Point: 536.6 ° C at 760 mmHg
Appearance: White crystall powder.
Assay:No less than 99%
Usage:Used for the prevention and treatment of hyperuricemia and gout.
|Category||Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.|
|Shelf life||2 years|
Lansoprazole is a proton-pump inhibitor (PPI) which inhibits the stomach's production of gastric acids.Lansoprazole is manufactured by a number of companies worldwide under several brand names. Lansoprazole is a proton-pump inhibitor (PPI) in the same pharmacologic class as omeprazole.Lansoprazole has been marketed for many years and is one of several PPIs available.Lansoprazole is a racemate 1:1-mixture of the enantiomers dexlansoprazole and levolansoprazole.
|Lansoprazole should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.|
Febuxostat is a new generation xanthine oxidase inhibitor developed by Tejin Co. (Japan,) used clinically for for long-term treatment of hyperuicemia (gout,) a new and highly effective non-purine selective inhibitor of xanthine oxidase. It is not recommended for gout patients without hyperuricemia.
|Appearance||White to off-white crystalline powder|
|Related Substances||Total impurities: NMT 0.1%
Maximum single impurity: NMT 0.3%
|Loss on drying (Dry it at 105ºC in an electric air blowing dryer till a constant weight)||NMT 1.0%|
|Residue on Ignition||NMT 0.1%|
|Heavy metal||NMT 20ppm|
|Assay (on dried basis)||98.0% ~ 102.0%|
Contact Person: bruce