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| CAS: | 19608-29-8 | Product Name: | CB-03-01 |
|---|---|---|---|
| Type: | Hair Growth | Appearance: | White Powder |
| Usage: | Hair Growth | Alias: | CB-03-01 |
| Assay: | 99% Min | Key Words: | CB-03-01 |
| High Light: | raw materials for pharma industry,intermediates in pharmaceuticals |
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High Purity CAS: 19608-29-8 CB-03-01 for Hair Growth CB-03-01
Quick Detail:
Introduction of hair growth raw materials CB-03-01
Product Name: CB-03-01
Purity: 98%min by HPLC
CAS No.: 19608-29-8
Appearance: White powder
M.W.: 402.531
M.F.: C24H34O5
CB-03-01 is a molecule that acts at the level of the skin androgen receptor, blocking dihydrotestosterone (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe for acne and androgenic alopecia. The results of these studies demonstrate that CB-03-01 appears to have potent anti-androgenic activity without significant local or systemic side effects.
Function of hair growth raw materials CB-03-01
Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen–specifically, an androgen receptor antagonist – which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
COA
| Items | Requirements | Results |
| Appearance: | White Powder | White Powder |
| Identification | ||
| HPLC | IR spectra is consistent with CRS | Conforms |
| Sulphated Ash | ≤0.1% | 0.01% |
| Loss on drying | ≤0.5% | 0.38% |
| Related substances |
Impurity A ≤0.1% Impurity B ≤0.2% Any other Impurity ≤0.1% All other Impurity A ≤0.2% |
<0.1% <0.2% <0.1% <0.2% |
|
Heavy metal Pb : Cadmium(Cd) : As : Hg: |
≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm |
<10ppm Conforms 0.3ppm Conforms Negative |
| Assay | ≥99% | 99.5% |
| Conclusion: | The product conforms to BP. | |
High Purity CAS: 19608-29-8 CB-03-01 for Hair Growth CB-03-01
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