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| Cas No.: | 30123-17-2 | Other Names: | S-1574 |
|---|---|---|---|
| Product NamRopivacainee: | Tianeptine Sodium Salt | Appearance: | White Powder |
| Assay: | 99% Tianeptine Sodium Salt | Grade: | Pharmaceutical Grade |
| Storage: | Cool Dried Storage | Application: | Pharmaceutical Raw Intermediates |
| High Light: | sleeping pill eszopiclone,zopiclone for anxiety |
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Tianeptine Sodium CAS 30123-17-2 For Antidepressant Pharmaceutical Grade 99% Purity
Details:
Product name: Tianeptine/Tianeptine sodium
CAS No: 30123-17-2
M.Wt: 458.93
Formula: C21H24ClN2NaO4S
Solubility: Soluble to 100 mM in water and to 10 mM in DMSO
Purity: 99% Min
Standard: EP8.0
Grade: Pharmaceutical grade
MESH: 80 mesh Screen
Storage: Desiccate at RT
Appearance: white powder
Sample order: 10 Grams
Delivery: Within 3-5 days
Shipping : By Express TNT/DHL with tracking number provided
Certificate of Analysis:
| TEST | SPECIFICATION | RESULT |
| Appearance | Light yellow to off-white crystals | Off-white crystals |
| Identification | 1-HNMR: Consistent with the standard | Conforms |
| IR: The IR absorption spectrum of the sample must be concordant with test Standard. | Conforms | |
| HPLC: The HPLC spectrum of the sample must be concordant with the standard substance. | Conforms | |
| Residue on ignition | NMT 0.2% | 0.02% |
| Solubility | Soluble In water and methanol | Conforms |
| Water | NMT 5.0% | 0.28% |
| Heavy Metals | NMT 20ppm | 5ppm |
| Related Substance | Any other impurity: NMT 0.10% | 0.05% |
| Total impurities: NMT 0.5% | 0.17% | |
| Residual Solvents | Acetone: NMT 0.5% | N.D. |
| Dichloromethane: NMT 0.06% | Confirms | |
| Assay(By HPLC) | 99.0% | 99.83% |
| Storage | Store in a tightly closed container in a cool and dry place, below 20℃. | |
| Conclusion | Confirm to standard EP8.0 | |
Description:
Tianeptine is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Function:
Tianeptine is antidepressant. The animal has: the hippocampus pyramidal cells increased spontaneous activity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampal neurons at sites of 5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness; cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving.
Application:
This product is a kind of psychiatric drugs, anti depressants; anti anxiety drugs, it can treat depression (mild, moderate or severe)
It is a kind of API for nervous system
Contact Person: Mr. Bruce Lee
Tel: +8618874586545
Fax: 86-27-8321-4688
