Tianeptine Sodium Salt Pharmaceutical Raw Material CAS 30123-17-2 For Nootropic Supplyment
|Place of Origin||China|
|Minimum Order Quantity||negotiable|
|Price||Inquiry for Negotiable|
|Packaging Details||1-2 kg / aluminum foil bag, 25kg/ drum, as required|
|Delivery Time||1-2days after payment received|
|Payment Terms||T/T bank, Western Union, Bitcoin, Etc|
|Supply Ability||100KG/ Month|
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|CAS||30123-17-2||Product Name||Tianeptine Sodium Salt|
|Type||Pharmaceutical Raw Materials||Appearance||White Powder|
|Usage||For Nootropic Supplyment||Alias||TIANEPTINE SODIUM|
|Assay||99%min||Key Words||Tianeptine Sodium|
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Top Quality API Tianeptine Sodium Salt CAS 30123-17-2 for Nootropic Supplyment
Product Name: Tianeptine sodium salt
Mol File: 30123-17-2.mol
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Sulfur & Selenium Compounds;Stablon, Coaxil, Tatinol;API;Inhibitors
Melting point : 1800C
Storage temp. : Desiccate at RT
Chemical Properties : White to Yellowish Powder
Usage : Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant
Usage : Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe).
Tianeptine Sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetie, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
|Product Name||Tianeptine sodium|
|Description||White to yellowish powder, very hygroscopic.||Off-white powder, very hygroscopic.|
|Solubility||Freetly soluble In water and methanol and dichloromethane||Complies|
|Identification||(1)By IR, To match with working standard||Complies|
|(2)It gives reaction of sodium||Complies|
|Impurities A||≤0.1%||Not detected|
|Related compounds||Any impurity ≤0.1%||<0.1%|
|Total impurities ≤0.4%||0.25%|
|Residual Solvents||Acetidin≤ 0.5%||Not detected|
|Dichloromethane≤ 0.06%||Not detected|
|Methanol≤ 0.3%||Not detected|
|Acetone ≤ 0.5%||Not detected|
|N, N-dimethylformamide≤0.088%||Not detected|
|Assay||99.0%-101.0%(On anhydrous basis)||99.98%|
|Conclusion||Conform to EP8.0|
99% Tianeptine Sodium Salt Manufacturer CAS 30123-17-2 For Nootropic Supplyment